mTORC1 and mTORC2 regulate distinct aspects of glutamatergic synaptic transmission.
Matthew P. McCabe, Erin R. Cullen, Caitlynn M. L. Barrows, Amy N. Shore, Katharine I. Tooke, Matthew C. Weston
This study investigates the distinct roles of mTORC1 and mTORC2 in glutamatergic synaptic transmission by genetically inactivating each complex in mouse neurons, revealing their specific effects on presynaptic and postsynaptic functions.
bioRxiv · Aug 15, 2019 · PreprintNeuroscience