Author

Amy N. Shore

University of VermontORCID 0009-0008-1958-5607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Matthew C. WestoniD· 3 shared Erin R. CulleniD· 2 shared Wayne N. FrankeliD· 2 shared Alshaima’a M. QuniesiD· 1 shared Brittany D. SpitznageliD· 1 shared C. David WeaveriD· 1 shared Caitlynn M. L. BarrowsiD· 1 shared Cathleen M. LutziD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersNeuroscience

Matthew C. WestonORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 11, 2023

Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons

Amy N. Shore, Keyong Li, Mona Safari…·Matthew C. Weston

This study examines how a KCNT1 gain-of-function variant affects SST and PV GABAergic neurons, revealing differential functional outcomes and potential pathogenic mechanisms in DEEs.

7 citations

mouseelectronic health records

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 5, 2020

The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity.

Amy N. Shore, Sophie Colombo, William F. Tobin…·Matthew C. Weston

The paper investigates how a gain-of-function K+ channel variant causes seizures by reducing inhibitory neuron excitability and increasing network hyperconnectivity.

2 citations

mouseelectronic health records

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 15, 2019

mTORC1 and mTORC2 regulate distinct aspects of glutamatergic synaptic transmission.

Matthew P. McCabe, Erin R. Cullen, Caitlynn M. L. Barrows…·Matthew C. Weston

This study investigates the distinct roles of mTORC1 and mTORC2 in glutamatergic synaptic transmission by genetically inactivating each complex in mouse neurons, revealing their specific effects on presynaptic and postsynaptic functions.

DOI 10.1101/731554

mouseexperimental assay

𝕏 PostBluesky