Emad N. Eskandar

This study shows that electrical stimulation of the human pulvinar can generate visual percepts and alter cortical activity in patients with epilepsy.

This study shows TIGIT expression in myeloid cells of the GBM microenvironment promotes immunosuppression, and its knockdown enhances T cell function via NLRP3 signaling.

The paper shows propofol causes alpha rhythms to shift from posterior to anterior in two distinct thalamocortical networks, disrupting sensory and cognitive function during loss of consciousness.

This study shows cortical ripples occur during human NREM sleep and waking with similar characteristics to hippocampal ripples, associated with upstates, spindles, and unit co-firing, suggesting a role in memory consolidation.

This paper shows that high-frequency ripples synchronize cortical activity across distant brain regions during sleep, waking, and memory recall, supporting the binding-by-synchrony theory.

This study examines ketamine-induced brain dynamics in humans using intracranial recordings, identifying oscillatory changes linked to antidepressant and dissociative effects.

The paper examines how stimulation location relative to grey and white matter affects single pulse electrical stimulation responses in the human brain, finding location and parameter-specific effects.

The paper identifies three distinct classes of cortical activity using high-density microelectrodes, showing they are modulated by stimuli and present across species.

The paper analyzes spindles in humans to show they create spatiotemporal patterns of neuronal co-firing that may support memory consolidation during NREM sleep.

This study investigates how the brain represents stimulus presence and modal identity using neural recordings from non-human primates, finding distinct spatiotemporal dynamics in S1 and PMv cortices.

This study identifies the cortical and thalamic generators of the human alpha rhythm, showing it originates in higher-order cortex and propagates to lower-order regions and thalamus.

This study uses state-space modeling and intracranial stimulation to modulate hidden emotional states during conflict resolution, showing bidirectional effects on behavior.

The paper analyzes neuronal activity in non-human primates under anesthesia to compare consciousness theories, finding convergent neurons show greater consciousness-related properties than integrative neurons.

This paper demonstrates that intracortical signals from areas distant from seizure onset can predict focal seizures with 90% accuracy using machine learning.

The paper identifies replay of waking cortical activity patterns during slow-wave sleep in humans and links them to sleep features like spindles and sharp-wave ripples, supporting memory consolidation theories.