Author

David W. Zhou

Brown UniversityORCID 0000-0002-9635-0472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:electronic health records· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Emad N. EskandariD· 2 shared Emery N. BrowniD· 2 shared Linda S. AglioiD· 2 shared Patrick L. PurdoniD· 2 shared Robert A. PeterfreundiD· 2 shared Sydney S. CashiD· 2 shared Aaron L. SampsoniD· 1 shared Andrés F. Salazar-GómeziD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersNeuroscience

Emad N. EskandarORCID

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3 papers

Recent·Most cited

Uncovering putative neural mechanisms of neurotherapeutic impacts on EEG using the Human Neocortical Neurosolver

Nicholas M. Tolley, David W. Zhou, Austin E. Soplata, Dylan Daniels, Katharina Duecker, Carolina Fernandez Pujol, Joyce Gao, Stephanie R. Jones

This paper demonstrates how physics-based neural simulations can interpret EEG biomarkers of neurotherapeutics by connecting localized EEG signals to multi-scale neural generators.

bioRxiv · Apr 13, 2026 · PreprintNeuroscience

Propofol disrupts alpha dynamics in distinct thalamocortical networks underlying sensory and cognitive function during loss of consciousness

Veronica S. Weiner, David W. Zhou, Pegah Kahali, Emily P. Stephen, Robert A. Peterfreund, Linda S. Aglio, Michele D. Szabo, Emad N. Eskandar, Andrés F. Salazar-Gómez, Aaron L. Sampson, Sydney S. Cash, Emery N. Brown, Patrick L. Purdon

The paper shows propofol causes alpha rhythms to shift from posterior to anterior in two distinct thalamocortical networks, disrupting sensory and cognitive function during loss of consciousness.

Proceedings of the National Academy of Sciences · Mar 10, 2023Peer-reviewedNeuroscience

Characterizing ketamine-induced dissociation using human intracranial neurophysiology: brain dynamics, network activity, and interactions with propofol

Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo A. Balanza, Angelique Christine Paulk, Rina Zelmann, Noam Peled, Daniel J. Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, Garth Rees Cosgrove, Ziv M. Williams, Robert Mark Richardson, , Patrick L. Purdon

This study examines ketamine-induced brain dynamics in humans using intracranial recordings, identifying oscillatory changes linked to antidepressant and dissociative effects.

bioRxiv · May 2, 2022 · PreprintNeuroscience