Thomas Henry

PRESCOTT predicts the functional impact of missense mutations using sequence and structural data, outperforming existing methods in variant classification and disease-specific mutation analysis.

This study compares the pathogenicity of Staphylococcus aureus and Streptococcus pyogenes isolates toward human myoblasts and keratinocytes, finding higher internalization and cytotoxicity by NSTI-SA in myoblasts.