BiophysicsbioRxivPreprint
Integrated Computational and Spectroscopic Analyses to unravel the Role of Cu(II) Coordination in Modulating Doxorubicin-DNA Binding
Dipanshu Ranjan Pattanayak, Aditya Dileep Kurdekar, Sai Manohar Chelli…·R Dharmaraj
This study uses computational and spectroscopic methods to show that Cu(II) coordination increases DOX-DNA binding affinity and alters DOX conformation to favor intercalation.
DOI 10.64898/2026.09.11.750536