Improved mouse models of the small intestine microbiota using region-specific sampling from humans
Rebecca Neal Culver, Sean Paul Spencer, Arvie Violette, Evelyn Giselle Lemus Silva, Tadashi Takeuchi, Ceena Nafarzadegan, Steven Kyle Higginbottom, Dari Shalon, Justin Laine Sonnenburg, Kerwyn Casey Huang
The paper develops improved mouse models of the small intestine microbiota using region-specific human intestinal sampling and in vitro culturing, showing increased diversity and reproducibility in colonization.
bioRxiv · Apr 24, 2024 · PreprintMicrobiology