Laminar Shear Stress Increases the Cytosolic Pool of PINK1 in Endothelial Cells and Enhances Mitophagic Sensitivity Toward Dysfunctional Mitochondria
Soon‐Gook Hong, Junchul Shin, Jason Saredy, Soo Young Choi, Hong Wang, Joon‐Young Park
This study shows laminar shear stress increases cytosolic PINK1 in endothelial cells, enhancing mitophagic sensitivity to dysfunctional mitochondria and improving cardiovascular health.
bioRxiv · Jun 21, 2025 · PreprintPhysiology