Integrated rational and evolutionary engineering of genome-reduced Pseudomonas putida strains empowers synthetic formate assimilation
Justine Turlin, Beau B. Dronsella, Alberto De Maria, Steffen N. Lindner, Pablo I. Nikel
The paper engineers genome-reduced Pseudomonas putida strains to assimilate formate as a carbon source using a modular approach and adaptive evolution, achieving faster growth and two distinct catabolic pathways.
Metabolic Engineering · Oct 31, 2022Peer-reviewedSynthetic Biology