Sequence adaptations satisfy the constraints of mitochondrial membrane protein evolution
Tarun Yadav, Jonathan H. Borowsky, Álvaro Jesús Narbona‐Pérez, Bhavya Soni, Corey Nathaniel Cunningham, James Carrington, Michael Grabe, Jared P. Rutter
The paper identifies aliphatic-to-threonine substitutions as a conserved adaptation in mitochondrial membrane proteins that balances hydrophilicity and hydrophobicity requirements.
bioRxiv · Aug 7, 2026 · PreprintBiochemistry