Discovering Matrix Adducts for Enhanced Metabolite Profiling with Stable Isotope-Labeled MALDI-MSI
Gerard Baquer, Miguel Bernús, Lluc Sementé, René J. M. van Zeijl, María García‐Altares, Bram Heijs, Omar Boutureira, Xavier Correig, Pere Ràfols
This study introduces a workflow using isotopic labeling to identify and remove matrix adducts in MALDI-MSI, improving metabolite annotation and tissue morphology interpretation.
bioRxiv · Jun 28, 2023 · PreprintBioinformatics