Gerard Baquer

Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT

The paper introduces INSIGHT, a platform for phosphoproteomic analysis of rare cell subpopulations, and applies it to study signaling changes in disseminated glioblastoma cells in vivo.

Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice

The paper develops a platform to trace 30 nitrogen isotope-labeled metabolites, revealing cell state-specific pyrimidine synthesis pathway preferences in primitive and differentiated cells.

Nanoparticle encapsulation enhances spatial distribution of Panobinostat to treat metastatic medulloblastoma via the intrathecal route

This study develops a nanoparticle system to deliver Panobinostat intrathecally for treating metastatic medulloblastoma, showing improved drug distribution and survival benefits in mice.

A pathogenic subpopulation of human glioma associated macrophages linked to glioma progression

This study identifies a pathogenic subpopulation of glioma-associated macrophages (mGAMs) linked to glioma progression through GRN analysis and functional validation.

Spatial Profiling of Metals through Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging

This paper introduces a MALDI MSI method to spatially profile metals in tissues, applying it to study embryogenesis, genetic disorders, and chemotherapy delivery.

Discovering Matrix Adducts for Enhanced Metabolite Profiling with Stable Isotope-Labeled MALDI-MSI

This study introduces a workflow using isotopic labeling to identify and remove matrix adducts in MALDI-MSI, improving metabolite annotation and tissue morphology interpretation.

rMSIcleanup: An open-source tool for matrix-related peak annotation in mass spectrometry imaging and its application to silver-assisted laser desorption/ionization

rMSIcleanup annotates and removes matrix-related peaks in MSI data, improving post-processing by reducing redundant signals.