Author

Murugan Kalimutho

Translational Research InstituteORCID 0000-0002-0772-8673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

George R. AmbalathingaliD· 1 shared Göknur GineriD· 1 shared Kum Kum KhannaiD· 1 shared Marco J. HeroldiD· 1 shared Prahlad V. RaningaiD· 1 shared Sivanandhini SankarasubramanianiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

George R. AmbalathingalORCID

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1 paper

Recent·Most cited

Thioredoxin reductase 3 inhibition sensitizes triple-negative breast cancer cells to EGFR inhibitors

Prahlad V. Raninga, Göknur Giner, Sivanandhini Sankarasubramanian, George R. Ambalathingal, Murugan Kalimutho, Marco J. Herold, Kum Kum Khanna

This study identifies TXNRD3 as a target to sensitize triple-negative breast cancer cells to EGFR inhibitors by enhancing EGFR activation and surface localization.

bioRxiv · Mar 16, 2025 · PreprintCancer Biology