The scaffold nucleoporin Nup188 undergoes liquid-liquid phase separation
Aswathy L B, Bhawna Burdak, Shrankhla Bawaria, Subhajit Das, Sejal Agarwal, Carl M. Jones, Akshaykumar B Chaudhari, Vidisha Tripathi, Kishal Roy, Atharv Tiwatane, Parashuram Sonawane, Shekhar C. Mande, Jomon Joseph, Sushma Nagaraja Grellscheid, Radha Chauhan
This study shows that the scaffold nucleoporin Nup188 can form liquid-liquid phase separation condensates, and Nup93 binding suppresses this process.
bioRxiv · Oct 7, 2026 · PreprintBiochemistry