Sushma Nagaraja Grellscheid

This study shows that the scaffold nucleoporin Nup188 can form liquid-liquid phase separation condensates, and Nup93 binding suppresses this process.

The paper sequenced Norwegian farmhouse yeasts to study their genetic diversity and domestication history, finding they form an early diverging lineage with distinct phylogenetic and population genetic characteristics.

This study investigates how filaments deform biomolecular condensate droplets and identifies physical mechanisms governing their shapes.

HIDE improves cell-type deconvolution by incorporating a cell hierarchy, showing better performance in simulations and applied to breast cancer data.

DynaMiCs integrates single-cell and bulk transcriptomics data to improve cell-type deconvolution and map population changes between phenotypes.

FlickerPrint measures interfacial tension and bending rigidity of biomolecular condensates and vesicles from confocal images using flicker spectroscopy, enabling scalable population-level analysis.

Deconomix deconvolves bulk transcriptomics data to estimate cell compositions, background contributions, and cell-type-specific gene regulation.

ADTD improves estimation of cellular compositions from bulk transcriptomics data by adapting reference profiles to the molecular environment and identifying hidden contributions.

This study reanalyzes the phylogenetic position of traditional Norwegian kveik yeast within Saccharomyces cerevisiae, finding it to be an ancient clade closer to the root of the species tree.

The paper identifies conserved ribosome stall sites across multiple species using ribosome profiling data, finding that specific amino acids facilitate stalling in RNA processing genes.