Diagnosis of Human Leptospirosis: High Resolution Melting Analysis for Direct Detection of Leptospira in the Early Stage of the Disease in a Clinical Setting
Lisa M. Esteves, Sara M. Bulhões, Claudia C. Branco, Teresa Carreira, Maria L. Vieira, Maria Gomes-Solecki, Luisa Mota-Vieira
The paper compares high resolution melting analysis with nested PCR and MAT for diagnosing leptospirosis, finding HRM detects Leptospira earlier than serologic tests.
bioRxiv · May 2, 2018 · PreprintMicrobiology