A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism
Linnea Österberg, Iván Domenzain, Julia Münch, Jens Nielsen, Stefan Hohmann, Marija Cvijović
The paper develops a hybrid modeling framework integrating Boolean and enzyme-constrained networks to study the interplay between nutrient signaling and metabolism in yeast, revealing new insights into their regulatory effects.
PLoS Computational Biology · Apr 9, 2021Peer-reviewedSystems Biology