Regulation of mitochondrial DNA homeostasis by a mitochondrial microprotein
Ikram Ajala, Damien Lipuma, Grégoire Bonnamour, Benoît Vanderperre
This study identifies AltSLC35A4, an AltORF-encoded protein, as a regulator of mitochondrial DNA homeostasis by interacting with actomyosin cytoskeletal components and affecting mtDNA spatial distribution.
bioRxiv · Feb 21, 2026 · PreprintBiochemistry