Systems BiologyBiogerontologyPeer-reviewed
The frailty syndrome as an emergent state of parallel dysregulation in multiple physiological systems
Ahmed Ghachem, Linda P. Fried, Véronique Legault…·Alan Arthur Cohen
This study investigates frailty as an emergent property of physiological system dysregulation using Mahalanobis distance in two older adult cohorts, finding partial support for breadth and nonlinearity of associations.
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