STING promotes homeostatic maintenance of tissues and confers longevity with aging
Jacob W. Hopkins, Katherine B. Sulka, Machlan Sawden, Kimberly A. Carroll, Ronald D. Brown, Stephen C. Bunnell, Alexander Poltorak, Albert Tai, Eric R. Reed, Shruti Sharma
This study shows that STING signaling maintains tissue homeostasis and promotes longevity by regulating immune fingerprints and macrophage function during aging.
bioRxiv · Apr 4, 2024 · PreprintImmunology