Eric R. Reed

The paper integrates six single-cell datasets to create a high-resolution atlas of HPV-negative HNSCC, revealing new cell populations and associations between transcriptional signatures and clinical outcomes.

This study identifies age and survival-related transcriptomic signatures in longevity-enriched cohorts using RNAseq data from blood samples.

The paper validates and expands a serum protein signature associated with APOE genotypes, identifying new protein associations and potential targets for Alzheimer's disease prevention.

The paper validates and expands a serum protein signature of extreme old age using LC-MS/MS, identifying 80 conserved proteins across platforms associated with aging pathways.

This study shows that STING signaling maintains tissue homeostasis and promotes longevity by regulating immune fingerprints and macrophage function during aging.

This paper introduces a method to identify conserved molecular features across non-independent omics studies by adjusting p-values to account for inter-study dependencies.

The paper identifies a Gabra2 variant that increases methamphetamine sensitivity using QTL analysis in mice and validates it with CRISPR correction.

The paper introduces K2Taxonomer, an unsupervised algorithm for identifying molecular subgroups in bulk and single-cell transcriptomics data, and applies it to breast cancer TILs to find a shared transcriptional program associated with better prognosis.

The paper identifies 5' UTR variants in Hnrnph1 that reduce 5' UTR usage and hnRNP H protein levels, linking these changes to reduced methamphetamine sensitivity.

This study evaluates a highly multiplexed RNA sequencing platform (SFL) and compares its performance to existing techniques, finding it outperforms 3DGE in coverage and differential gene expression detection.

The paper identifies a major QTL on chromosome 7 associated with acute thermal nociception in C57BL/6 mouse substrains.