Author

Bharat Burman

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-0824-1357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:CITE-seq· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew McPhersoniD· 2 shared Andrew T. ChowiD· 2 shared Benjamin D. GreenbaumiD· 2 shared Nicholas CegliaiD· 2 shared Nicole RuskiD· 2 shared Sohrab P. ShahiD· 2 shared Viktoria BojilovaiD· 2 shared Zachary M. SethnaiD· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBioinformatics

Andrew McPhersonORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedJul 20, 2023

GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information.

Nicholas Ceglia, Zachary M. Sethna, Samuel S. Freeman…·Andrew McPherson

GeneVector uses mutual information-based dimensionality reduction to identify transcriptional programs and classify cell types across single-cell RNA-seq datasets.

10 citations

scRNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 1, 2022

TCRi: Information theoretic metrics for single cell RNA and TCR sequencing in cancer

Nicholas Ceglia, Zachary M. Sethna, Yuval Elhanati…·Benjamin D. Greenbaum

This paper introduces TCRi, an information theoretic framework to analyze TCR and gene expression data from cancer patients, showing improved characterization of clonotypes and their phenotypic changes post-therapy.

2 citations

humanscRNA-seq

𝕏 PostBluesky