Author

Andrew T. Chow

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-1151-2450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Benjamin D. GreenbaumiD· 3 shared Andrew McPhersoniD· 2 shared Bharat BurmaniD· 2 shared Nicholas CegliaiD· 2 shared Nicole RuskiD· 2 shared Samuel S. FreemaniD· 2 shared Sohrab P. ShahiD· 2 shared Viktoria BojilovaiD· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioinformatics

Benjamin D. GreenbaumORCID

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3 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedJul 20, 2023

GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information.

Nicholas Ceglia, Zachary M. Sethna, Samuel S. Freeman…·Andrew McPherson

GeneVector uses mutual information-based dimensionality reduction to identify transcriptional programs and classify cell types across single-cell RNA-seq datasets.

10 citations

scRNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 1, 2022

TCRi: Information theoretic metrics for single cell RNA and TCR sequencing in cancer

Nicholas Ceglia, Zachary M. Sethna, Yuval Elhanati…·Benjamin D. Greenbaum

This paper introduces TCRi, an information theoretic framework to analyze TCR and gene expression data from cancer patients, showing improved characterization of clonotypes and their phenotypic changes post-therapy.

2 citations

humanscRNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 21, 2022

Integrative Analysis of Checkpoint Blockade Response in Advanced Non-Small Cell Lung Cancer

Arvind Ravi, Justin F. Gainor, Monica B. Arniella…·Matthew David Hellmann

This study identifies molecular and immune features associated with response to anti-PD-(L)1 therapy in NSCLC using a cohort of 393 patients.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky