Deficits in neuronal architecture but not over-inhibition are main determinants of reduced neuronal network activity in a mouse model of overexpression of Dyrk1A
Linus Manubens-Gil, Meritxell Pons‐Espinal, Thomas Gener, Inmaculada Ballesteros‐Yáñez, María Martínez de Lagrán, Mara Dierssen
This study investigates how Dyrk1A overexpression in mice affects neuronal network activity, finding that structural deficits, not over-inhibition, primarily impair network function.
Cerebral Cortex · Nov 7, 2023Peer-reviewedNeuroscience