Metabolic PCTA-Based Shift Reagents for the Selective Detection of Extracellular Lactate Using CEST MRI
Remy Chiaffarelli, Pedro F. Cruz, Jonathan M. Cotton, Tjark Kelm, Slade Lee, Mohammad Ghaderian, Max Zimmermann, Carlos F. G. C. Geraldes, Paul E. Jurek, André F. Martins
This paper introduces PCTA-based shift reagents for detecting extracellular lactate via CEST MRI, showing feasibility in vitro and safety in vivo.
JACS Au · Feb 10, 2025Peer-reviewedBiochemistry