Differential spreading behaviors of Nodal signalling molecules in the extracellular space cooperatively shape left-right asymmetry
Takafumi Ikeda, Toru Kawanishi, Yusuke Mii, Taijiro Yabe, José L. Pelliccia, Rebecca D. Burdine, Hiroyuki Takeda
The paper shows how Nodal and Gdf1 spread freely while Dand5 is immobilized, shaping left-right asymmetry in zebrafish embryos.
bioRxiv · Aug 13, 2025 · PreprintDevelopmental Biology