Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies
David J. Wooten, Jorge Gómez Tejeda Zañudo, David Murrugarra, Austin M. Perry, Anna I. Dongari‐Bagtzoglou, Reinhard Laubenbacher, Clarissa J. Nobile, Réka Albert
This study builds a Boolean model of the C. albicans yeast-to-hyphal transition, identifies key control strategies, and validates them experimentally.
PLoS Computational Biology · Mar 29, 2021Peer-reviewedSystems Biology