Clarissa J. Nobile

The paper presents an optimized protocol for infecting planarians with Candida albicans to study fungal pathogenesis and host defense mechanisms.

This study characterizes transcriptomic changes in Coccidioides posadasii across different morphologies using RiboMarker-enhanced RNA sequencing, revealing small RNA and fragment expression patterns associated with life stage transitions.

This study compares four CRISPR-Cas9 systems for genome editing in Candida auris, finding significant differences in efficiency and integration patterns.

This paper develops an ODE-based GRN inference method using dynamic transcriptional data and validates it on synthetic yeast and Candida albicans GRNs.

This study builds a Boolean model of the C. albicans yeast-to-hyphal transition, identifies key control strategies, and validates them experimentally.

This study identifies two C. albicans proteins essential for epithelial infection of planarians and describes a multi-system host response involving stem cells and distinct tissues.