Author

Hao Wu

Second Military Medical UniversityORCID 0000-0002-0858-8430Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hao Wu24 papers · University of Pennsylvania

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Claude FéreciD· 2 shared Emmanuelle MassoniD· 2 shared Jian‐Min CheniD· 2 shared Wen‐Bin ZouiD· 2 shared Zhuan LiaoiD· 2 shared Arnaud BoullingiD· 1 shared Baohua MaiD· 1 shared Cédric Le MaréchaliD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Claude FérecORCID

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3 papers

Recent·Most cited

Combining full-length gene assay and SpliceAI to interpret the splicing impact of all possible SPINK1 coding variants

Hao Wu, Jin‐Huan Lin, Xin‐Ying Tang, Gaëlle Marenne, Wen‐Bin Zou, Sacha Schutz, Emmanuelle Masson, Emmanuelle Génin, Yann Fichou, Gérald Le Gac, Claude Férec, Zhuan Liao, Jian‐Min Chen

The paper combines full-length gene splicing assay and SpliceAI to analyze splicing effects of SPINK1 coding variants, finding less than 2% of variants significantly impact splicing.

Human Genomics · Feb 27, 2024Peer-reviewedGenetic & Genomic Medicine

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy

Hui Zhang, Chan Li, Qingyang Liu, Jingmei Li, Hao Wu, Rui Xu, Yidan Sun, Ming Y. Cheng, Xiaoe Zhao, Meng‐Hao Pan, Qiang Wei, Baohua Ma

This study shows that C-type natriuretic peptide improves oocyte quality in aged mice by reducing oxidative damage and suppressing excessive mitophagy through the cAMP/PKA pathway.

eLife · Oct 20, 2023Peer-reviewedDevelopmental Biology

Genetic analysis of the STIM1 gene in chronic pancreatitis

Emmanuelle Masson, Wen‐Bin Zou, Claudia Ruffert, Vanessa Holste, Patrick Michl, Joachim Mössner, Maren Ewers, Helmut Laumen, Hao Wu, Daizhan Zhou, Zhao‐Shen Li, Dong Su Yu, Arnaud Boulling, Cédric Le Maréchal, D.N. Cooper, , Claude Férec

The paper identifies rare STIM1 coding variants enriched in chronic pancreatitis patients compared to controls, suggesting a potential genetic association.

bioRxiv · Jul 8, 2019 · PreprintGenetics