A standardized atlas of human bronchoalveolar lavage cells built using scalable ensemble annotation and cross-study robust markers
Yushan Hu, Ziying Liu, Kailun Bai, Belaid Moa, Janice M. Leung, Firoozeh V. Gerayeli, Don D. Sin, Xiaojian Shao, Xuekui Zhang
The paper constructs a standardized BAL scRNA-seq atlas using BAL-EA, a novel annotation framework, revealing disease-associated shifts in COPD and validating findings in COVID-19 datasets.
bioRxiv · Jan 9, 2026 · PreprintGenomics