Author
University of British ColumbiaORCID 0000-0003-1682-6483Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Josh P Dyce, Ana I. Hernández Cordero, Michael Steffen Kobor…·Bradley S. Quon
This study shows that ETI treatment in CF patients reduces epigenetic age acceleration, linked to inflammation and disease activity.
Yushan Hu, Ziying Liu, Danielle Tsao…·Xuekui Zhang
Systematic benchmarking reveals pseudo-bulk biases and provides practical fixes for accurate RNA deconvolution.
Yushan Hu, Ziying Liu, Kailun Bai…·Xuekui Zhang
The paper constructs a standardized BAL scRNA-seq atlas using BAL-EA, a novel annotation framework, revealing disease-associated shifts in COPD and validating findings in COVID-19 datasets.
Firoozeh V. Gerayeli, Stephen B Milne, Chen Xi Yang…·Don D. Sin
The paper develops a rapid, minimal-handling protocol for preparing single-cell suspensions from bronchial brush specimens for scRNA-seq to improve airway disease research.
Aniqa Shahid, Bradley R. Jones, J.S.W. Yang…·Zabrina L. Brumme
This study analyzes HIV proviral diversity and compartmentalization in blood and lung during suppressive ART, finding shared sequences and limited genetic compartmentalization.
Chen Xi Yang, Henry Shi, Irving Ding…·Ma’en Obeidat
The paper identifies sex-specific transcriptomic responses to smoking in human airway epithelium, revealing sexually dimorphic gene modules associated with autophagy and immune response pathways.