Author

Burak Kaynak

University of PittsburghORCID 0000-0002-0897-2037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

İvet BahariD· 1 shared James KriegeriD· 1 shared Mary Hongying ChengiD· 1 shared Moshe ArditiiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

İvet BaharORCID

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1 paper

Recent·Most cited

Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment

Mary Hongying Cheng, James Krieger, Burak Kaynak, Moshe Arditi, İvet Bahar

Modeling indicates N501Y strengthens ACE2 binding while K417N and E484K break two interface salt bridges, leaving 501.V2 affinity near wildtype but weakening several monoclonal antibodies.

bioRxiv · Jan 10, 2021 · PreprintMolecular Biology