Author

James Monypenny

King's College LondonORCID 0000-0002-0968-9268Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angela L. Caipa Garcia· 1 shared Ceri Savage· 1 shared Gregory Weitsman· 1 shared Marco FoianiiD· 1 shared Tony NgiD· 1 shared Xiaolan JiangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Angela L. Caipa Garcia

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1 paper

Recent·Most cited

TOPII-targeting and MUS81 deficiency sensitise HER2-low tumour models to T-DXd

James Monypenny, Ceri Savage, Angela L. Caipa Garcia, Xiaolan Jiang, Gregory Weitsman, Marco Foiani, Tony Ng

This study identifies TopII targeting and MUS81 deficiency as sensitizers to T-DXd in HER2-low tumour models, showing increased cytotoxicity and DNA damage.

bioRxiv · Aug 6, 2026 · PreprintCancer Biology