Autologous host-pathogen pairing enhances early immune responses and bacterial growth control in tuberculosis in vitro granuloma model
Charlotte Genestet, Chloé Bourg, Elisabeth Hodille, Olivier Bahuaud, Florence Ader, Oana Dumitrescu
This study shows that autologous host-pathogen pairing in an in vitro granuloma model leads to lower bacterial loads and increased Th1 cytokines at 7 days but not later, highlighting the role of host-pathogen interactions in TB.
bioRxiv · Dec 20, 2024 · PreprintMicrobiology