Development of a Matrix-Matched Calibration Curve for Multi-Site Quantification of Neu5Gc-Bearing N-Glycans
Nicholas J. DeBono, Edward S. X. Moh, Jessica Poole, Nicolle H. Packer, Christopher J. Day, Michael P. Jennings, Daniel Kolarich, Christopher Ashwood
This paper develops a matrix-matched calibration curve for quantifying Neu5Gc-bearing N-glycans across multiple sites, showing LC-MS outperforms DMB-LC-FLR in dynamic range and sensitivity.
bioRxiv · Jul 15, 2026 · PreprintBiochemistry