Zhou Zhou

This study uses single-nucleus multiomic and spatial transcriptomic data to identify gene regulatory dynamics and key regulators in human aortic root tissue under healthy and Marfan syndrome conditions.

The paper characterizes CNCC derivatives' transcriptomic states and lineage transitions during development, identifying new subpopulations and molecular signatures.

The paper uses single-cell RNA-seq to study cardiac outflow tract development in mice, identifying new cell lineages and transitions, including myocardial to VSMC trans-differentiation.