An AlphaFold guided model for the evolution of the CaMKII interactome
Salman Tausene Khwaja, Maham Hamid, Thomas S. Reese, Shahid Khan
The paper analyzes the evolution of the CaMKII interactome across species using 3D structures and transcriptome data, finding conservation of activation machinery and reduced co-expression in simpler organisms.
bioRxiv · Aug 21, 2025 · PreprintNeuroscience