BioengineeringbioRxivPreprint
RFdiffusion Exhibits Low Success Rate in De Novo Design of Functional Protein Binders for Biochemical Detection
Bruce Jiang, Xiaoxiao Li, Amber Guo…·Junhua Wu
This study evaluates RFdiffusion's ability to design functional protein binders for six targets, finding limited success with only two Strep-Tag II binders outperforming streptavidin.