ImmunologyJournal of Clinical InvestigationPeer-reviewed
Activated STING in the thymus alters T cell development and selection leading to autoimmunity
Zimu Deng, Christopher S. Law, Santosh Kurra…·Anthony K. Shum
This study shows STING activation in thymic epithelial cells disrupts T cell selection and promotes autoimmunity by altering interferon signaling and macroautophagy.