Author

Christopher S. Law

University of California, San FranciscoORCID 0009-0005-4516-3844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Anthony K. ShumiD· 3 shared Alaa OthmaniD· 1 shared Anja KerksiekiD· 1 shared Anne I. SperlingiD· 1 shared Antoine RimbertiD· 1 shared Arnold von EckardsteiniD· 1 shared Bart van de SluisiD· 1 shared Brian WoodsiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

Anthony K. ShumORCID

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3 papers

Recent·Most cited

Cell BiologyAtherosclerosisPeer-reviewedAug 25, 2026

The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion

Grigorios Panteloglou, Jérôme Robert, Marieke Smit…·Arnold von Eckardstein

This study identifies COPI coatomer subunits that regulate LDL receptor activity, apoB secretion, and hepatic lipid storage, with genetic variants linked to elevated LDL-C levels.

DOI 10.1016/j.atherosclerosis.2026.121887

humanmouse

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ImmunologyJournal of Clinical InvestigationPeer-reviewedJun 26, 2025

Activated STING in the thymus alters T cell development and selection leading to autoimmunity

Zimu Deng, Christopher S. Law, Santosh Kurra…·Anthony K. Shum

This study shows STING activation in thymic epithelial cells disrupts T cell selection and promotes autoimmunity by altering interferon signaling and macroautophagy.

10 citations

mousescRNA-seq

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Molecular BiologybioRxivPreprintApr 24, 2023

PhIP-Seq uncovers novel autoantibodies and unique endotypes in interstitial lung disease

Vaibhav Upadhyay, Young me Yoon, Sara E. Vazquez…·Anthony K. Shum

This study uses PhIP-Seq to identify novel autoantibodies in ILD patients, revealing a new molecular endotype associated with inflammation and fibrosis.

3 citations

humanproteomics

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