A systematic analysis of brain tissue response to microelectrode material and size with single-cell spatial transcriptomics
Cort H. Thompson, Anirban Chakraborty, Lauren C. Wade-Kleyn, Mark A. Reimers, Erin K. Purcell
This study uses single-cell spatial transcriptomics to analyze the brain's response to different microelectrode materials and sizes in rats, finding that electrode dimensions have a greater impact on tissue response than material type.
bioRxiv · Mar 16, 2026 · PreprintNeuroscience