Erin K. Purcell

This study investigates how L-DOPA-induced dyskinesia (LID) relates to microstructural changes in brain circuits, finding brainwide alterations beyond the nigrostriatal system.

This study uses single-cell spatial transcriptomics to analyze the brain's response to different microelectrode materials and sizes in rats, finding that electrode dimensions have a greater impact on tissue response than material type.

This paper develops and tests all-diamond boron-doped microelectrodes for neurochemical sensing using fast-scan cyclic voltammetry, showing improved detection of serotonin compared to dopamine.

The paper compares gene expression in reactive astrocyte culture models to spatial transcriptomics data from implanted devices in rat brains, identifying shared genes and biomarkers of the foreign body response.