Thuy T. M. Ngo

GLORB: Robust Bayesian inference for differential expression underglobal expression shifts

GLORB improves differential expression analysis by accounting for global expression shifts, outperforming existing methods in scenarios with widespread upregulation or downregulation.

CSF-Seq enables transcriptome-wide profiling of cerebrospinal fluid and identifies prognostic signature of leptomeningeal disease

CSF-Seq profiles cerebrospinal fluid transcriptomes to identify a prognostic gene signature for leptomeningeal disease.

Loss of cell cycle gatekeeping by 1 CNOT3 impairs hematopoietic stem and progenitor cell division and repopulating activity

This study shows that CNOT3 deletion in HSCs causes anemia, reduced bone marrow cellularity, and impaired hematopoietic reconstitution.

Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles

The paper analyzes cf-mRNA in EVs and non-vesicular carriers from cancer patients and healthy donors, finding EVs selectively enrich cf-mRNA associated with specific biological pathways.