Trans-ethnic polygenic analysis supports genetic overlaps of lumbar disc degeneration with height, body mass index, and bone mineral density
Xueya Zhou, Ching‐Lung Cheung, Tatsuki Karasugi, Jaro Ilari Karppinen, Dino Samartzis, Yi‐Hsiang Hsu, Timothy Shin Heng Mak, You‐Qiang Song, Kazuhiro Chiba, Yoshiharu Kawaguchi, Yan Li, Danny Tat-Ming Chan, Kmc Cheung, Shiro Ikegawa, Kathryn S.E. Cheah, Pak Chung Sham
The paper uses polygenic scores to show genetic overlaps between lumbar disc degeneration and height, BMI, and BMD in Chinese and Japanese cohorts.
Frontiers in Genetics · Aug 3, 2018Peer-reviewedGenetics