Ching‐Lung Cheung

The paper identifies macrophages as key mediators linking aging and osteoporosis using genetic and single-cell analyses, revealing TGFB1 and HNRNPUL1 as critical regulators.

This study identifies 33 genetic variants associated with trabecular bone score (TBS) and finds a potential causal link between TBS and fracture risk independent of bone mineral density.

This study identifies shared and distinct ultra-rare genetic risk factors for epilepsy subtypes using whole-exome sequencing of 20,979 patients and 33,444 controls.

This study performs GWAS on BMD traits and fracture risk using 30,000 UK Biobank samples, identifies novel loci, and prioritizes drug targets for osteoporosis prevention.

This study performs a meta-analysis of GWAS to identify new genetic loci associated with all-cause and vascular dementia, revealing shared and distinct risk factors.

The paper uses polygenic scores to show genetic overlaps between lumbar disc degeneration and height, BMI, and BMD in Chinese and Japanese cohorts.