Structural model of the blood protein vitronectin bound to lipid and HDL
Kyungsoo Shin, William Brown, Ye Tian, Tata Gopinath, Andrey A. Bobkov, Fabrizio Marinelli, Francesca M. Marassi
This study identifies a hydrophobic groove on vitronectin's HX domain that binds phospholipids and mediates its association with HDL through structural modeling and simulations.
bioRxiv · Nov 1, 2025 · PreprintBiophysics