Author

Fabrizio Marinelli

Medical College of WisconsinORCID 0000-0003-0044-6718Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrey A. BobkoviD· 1 shared Daniel Joseph DeredgeiD· 1 shared Francesca M. MarassiiD· 1 shared Kyungsoo ShiniD· 1 shared Sandra Byju· 1 shared Tata GopinathiD· 1 shared Vincent M. LoweiD· 1 shared William BrowniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperBiophysics

Andrey A. BobkovORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 29, 2026

Multi-Ensemble Reweighting Enables Structural Interpretation of Differential HDX-MS

Sandra Byju, Vincent M. Lowe, Daniel Joseph Deredge, Fabrizio Marinelli

This paper introduces a multi-ensemble reweighting method for HDX-MS data to improve structural interpretation by accounting for deuterium loss, showing better accuracy than conventional methods.

DOI 10.64898/2026.10.28.762400

proteomicsstatistical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintNov 1, 2025

Structural model of the blood protein vitronectin bound to lipid and HDL

Kyungsoo Shin, William Brown, Ye Tian…·Francesca M. Marassi

This study identifies a hydrophobic groove on vitronectin's HX domain that binds phospholipids and mediates its association with HDL through structural modeling and simulations.

DOI 10.1101/2025.11.01.685992

humanprotein structure

𝕏 PostBluesky