Tata Gopinath

Structure-activity of outer membrane proteins in native bacterial membrane vesicles by solid-state NMR

This paper uses solid-state NMR to analyze the structure and activity of outer membrane proteins in native bacterial vesicles, showing their functionality and interactions with host ligands.

Structural model of the blood protein vitronectin bound to lipid and HDL

This study identifies a hydrophobic groove on vitronectin's HX domain that binds phospholipids and mediates its association with HDL through structural modeling and simulations.

In situ NMR reveals a pH sensor motif in an outer membrane protein that drives bacterial vesicle production

This paper identifies a pH-sensing motif in PagC, an outer membrane protein, that drives bacterial vesicle production and aggregation at acidic pH using in situ NMR and EM.

Solid state NMR spectral editing of histidine, arginine and lysine using Hadamard encoding

This paper introduces a Hadamard encoding method for multi-dimensional solid-state NMR spectral editing of protein sidechains, enabling unambiguous detection of signals from basic amino acids and their bound water molecules.