BiophysicsAdvanced SciencePeer-reviewed
Lipid-facilitated opening of the ADAM10 sheddase revealed by enhanced sampling simulations
Adrien Schahl, Nandan Haloi, Marta Carroni…·Rebecca J. Howard
This study uses simulations to show that phosphatidylserine induces conformational changes in ADAM10, leading to its activation and reduced antibody binding.
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