Quentin James Sattentau

This study investigates the effects of TMEM30A loss on immune cell membrane dynamics, revealing PS externalization, proteome reorganization, and glycocalyx remodeling with implications for immune therapy.

This study uses simulations to show that phosphatidylserine induces conformational changes in ADAM10, leading to its activation and reduced antibody binding.

This study shows that chemical cross-linking with EDC stabilizes HIV-1 Env trimers without significant structural distortion, improving their stability, morphology, antigenicity, and immunogenicity for vaccine development.